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Can I take Alogliptin and Bisoprolol together?

Drug interaction guide

Taking bisoprolol with alogliptin may occasionally hide the warning signs of low blood sugar (hypoglycaemia). It can also slightly increase the risk of your blood sugar dropping too low.

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Why this happens

Bisoprolol is a beta-blocker. These medicines can mask the physical symptoms of low blood sugar, such as a fast heartbeat or tremors. Additionally, beta-blockers can sometimes interfere with how the body releases glucose, which may enhance the blood-sugar-lowering effect of alogliptin.

What you should do

You can take these medicines together, but you should be aware that you might not feel the usual 'shaky' or 'racing heart' sensations if your blood sugar drops. Pay closer attention to other signs of low blood sugar, such as sweating, hunger, or blurred vision. Monitor your blood glucose levels regularly as advised by your doctor.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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