Can I take Ramipril and Vitamin C together?

Why this happens

Ramipril is an ACE inhibitor used for blood pressure, and Vitamin C is a water-soluble vitamin. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.

You can continue to take both as prescribed or recommended. As with any supplement, it is best to stick to the recommended daily allowance unless your doctor has advised otherwise.

Pregnancy

Do not take ramipril if you are pregnant or planning to become pregnant, as it can cause serious harm or death to an unborn baby.

Angioedema (Severe swelling)

Ramipril can cause a rare but serious allergic reaction involving sudden swelling of the face, lips, tongue, or throat (angioedema). If this occurs, stop taking the medicine and seek emergency medical help immediately. This risk is higher in people of African or Caribbean descent.

Kidney stones (renal calculi)

High doses of vitamin C can increase the amount of oxalate in your urine, which significantly raises the risk of developing kidney stones, especially if you have had them before.

G6PD deficiency

Very high doses of vitamin C can cause oxidative stress and lead to the breakdown of red blood cells (haemolysis) in individuals with G6PD deficiency.

Alcohol

It is best to avoid or strictly limit alcohol while taking ramipril. Alcohol can increase the blood pressure-lowering effect of ramipril, which may make you feel dizzy, lightheaded, or faint, especially when you first start the medicine or move to a higher dose.

Salt substitutes and high-potassium foods

Ramipril can increase the levels of potassium in your blood. You should avoid using salt substitutes that contain potassium (such as Lo-Salt) and speak to your doctor before significantly increasing your intake of high-potassium foods like bananas, spinach, or pulses. High potassium levels can affect your heart rhythm.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.