Can I take Solifenacin and Vitamin D together?

Why this happens

Solifenacin is a medicine used to treat an overactive bladder, and vitamin D is a fat-soluble vitamin used for bone health. They are processed by the body through different pathways and do not interfere with how the other works.

You can continue to take both as prescribed. Always inform your doctor or pharmacist of all supplements you are taking to ensure your records are up to date.

Glaucoma

Do not take solifenacin if you have narrow-angle glaucoma, as it can increase the pressure in your eyes and worsen the condition.

Urinary retention

Do not take solifenacin if you have difficulty emptying your bladder (urinary retention), as it may make this problem worse.

Hypercalcaemia (high blood calcium)

Do not take vitamin D if you have high levels of calcium in your blood or urine, as it can lead to serious kidney damage and heart rhythm problems.

Alcohol

It is best to avoid or strictly limit alcohol while taking solifenacin. Both alcohol and solifenacin can cause drowsiness and blurred vision; combining them increases the risk of these side effects and may impair your coordination.

Grapefruit Juice

Grapefruit juice can increase the level of solifenacin in your blood, which may increase the risk of side effects such as dry mouth, constipation, and blurred vision. It is best to avoid drinking large amounts of grapefruit juice.

Caffeine (Coffee, Tea, Energy Drinks)

You should limit your intake of caffeine. Solifenacin is used to treat an overactive bladder, but caffeine is a natural diuretic and bladder irritant that can worsen symptoms like urgency and frequency, potentially making your medication less effective.

High-fat meals

Vitamin D is a fat-soluble vitamin. It is best absorbed by your body when taken with a meal that contains some fat (such as avocado, nuts, or dairy).

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.