Flurbiprofen tablets for pain and inflammation

About flurbiprofen

What is flurbiprofen used for?

Flurbiprofen is a type of anti-inflammatory painkiller called non-steroidal anti-inflammatory drugs (NSAIDs).

It is used to treat painful conditions such as arthritis, sprains and strains, period (menstrual) pain, and migraine pain. It is also prescribed to ease pain after surgical operations.

Flurbiprofen is also available as eye drops and as throat lozenges.

How does flurbiprofen work?

Flurbiprofen works by blocking COX enzymes in the body. These enzymes help produce prostaglandins, chemicals that cause pain and inflammation at injured areas.

When flurbiprofen blocks COX enzymes, fewer prostaglandins are made, so pain and inflammation decrease.

Side effects of flurbiprofen

Common side effects of flurbiprofen include:

• Indigestion.

• Heartburn (reflux).

• Stomach pain.

• Feeling sick.

• Being sick (vomiting).

• Diarrhoea.

• Constipation.

• Tiredness.

• Fluid retention (oedema).

You will find a full list of side effects in the manufacturer's information leaflet supplied with your medicine.

The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any side effects continue or become troublesome.

How to manage flurbiprofen side effects

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for further advice.

Who should not take flurbiprofen?

Some medicines aren’t suitable for everyone. Before taking flurbiprofen, your doctor needs to know:

• If you have asthma or any other allergic disorder.

• If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.

• If you are pregnant, trying for a baby, or breastfeeding.

• If you are under 12 or over 65 years of age.

• If you have liver or kidney problems.

• If you have a heart condition, or a problem with your blood vessels or circulation.

• If you have high blood pressure.

• If you have ever had blood clotting problems.

• If you have high blood sugar or cholesterol levels.

• If you are a smoker.

• If you have a connective tissue disorder, such as systemic lupus erythematosus (an inflammatory condition also called lupus, or SLE).

• If you are taking any other medicines such as over-the-counter medicines as well as herbal and complementary medicines.

• If you have ever had an allergic reaction to any other NSAID (such as aspirin, naproxen, diclofenac, and ibuprofen), or to any other medicine.

How to take flurbiprofen

• Read the leaflet that comes with the medicine before you start. It explains how flurbiprofen works and lists possible side effects.

• Take flurbiprofen exactly as prescribed. Tablets come in 50 mg and 100 mg strengths.

  • For period pain, this is usually 50-100 mg every 4-6 hours as needed.

  • For other conditions, the usual dose is 150-200 mg per day, split into doses.

• Do not take more than 300 mg in one day.

• You can take flurbiprofen before meals, but it’s best to take it with food or just after eating. This helps protect your stomach and reduces indigestion and irritation.

• Most people find it helps to swallow the tablets with a drink of water.

• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

Getting the most from your treatment

• Your doctor will use the lowest dose for the shortest time to reduce side effects. If you need flurbiprofen long-term, you may be given another medicine to protect your stomach.

• Keep regular check-ups so your doctor can monitor how you’re doing, especially if you take it for a long time.

• If you have asthma, flurbiprofen may worsen breathing symptoms. Stop taking it and see your doctor if this happens.

• Before buying other medicines, check with a pharmacist. Do not take flurbiprofen with other anti-inflammatory painkillers, including some cold and flu products.

• Tell your doctor or dentist you are taking flurbiprofen before any treatment or surgery.

How to store flurbiprofen

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Frequently asked questions

How long does it take for flurbiprofen to work?

Flurbiprofen usually starts to work within 30-60 minutes of taking a dose. Pain relief and reduced inflammation typically improve during this time, with the full effect felt after a few hours.

Can you drink alcohol with flurbiprofen?

You should avoid drinking alcohol when taking flurbiprofen as it can increase the risk of stomach irritation, indigestion, ulcers, or bleeding, especially if flurbiprofen is taken regularly or at higher doses.

Is it safe to take flurbiprofen during pregnancy?

Flurbiprofen is not recommended during pregnancy, particularly in the third trimester, as it can harm the unborn baby and cause complications. Let your doctor know if you are pregnant or are planning on becoming pregnant.