Ipratropium nasal spray
Rinaspray
Peer reviewed by Dr Colin Tidy, MRCGPLast updated by Michael Stewart, MRPharmSLast updated 19 Apr 2026
Meets Patient’s editorial guidelines
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Ipratropium nose spray is used to help stop a runny nose.
Use two sprays into each nostril, two or three times a day.
The most common side effects are dryness and irritation of the nose or throat, mild nosebleeds, and headache.
At a glance
Ipratropium nasal spray is used to treat rhinorrhoea, commonly known as a runny nose.
It works by blocking mucus glands in the nose to reduce discharge.
Common side effects include mild nosebleeds, dry or irritated nose or throat, and headache.
Do not spray ipratropium near your eyes; wash your eyes with warm water if contact occurs.
You should tell your doctor if you have kidney problems, glaucoma, or cystic fibrosis before using.
The usual dose is two sprays into each nostril, two or three times daily.
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Overview
Type of medicine | An antimuscarinic |
Used for | Rhinorrhoea (runny nose) |
Also called | Rinaspray® (ipratropium); |
Available as | Nasal spray |
What is ipratropium used for?
Back to contentsIpratropium nasal spray is given to help stop rhinorrhoea. Rhinorrhoea is a thin watery discharge of mucus from the nose. It is often described as a 'runny nose'.
It may be caused by an allergy, or because of other reasons such as changes in atmosphere or temperature.
Ipratropium is also available as an inhaler or as nebules for the treatment of breathing problems. A separate leaflet called Ipratropium - a bronchodilator has more information about this.
How does ipratropium work?
Ipratropium blocks the action of mucus-making glands in your nose, and this reduces the amount of discharge produced.
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Side effects of ipratropium
Back to contentsCommon side effects of ipratropium include:
Mild nosebleeds.
Dry or irritated nose.
Dry or irritated throat.
Headache.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
How to manage ipratropium side effects
Back to contentsThe unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common ipratropium nasal spray side effects (these affect fewer than 1 in 10 people) | What can I do if I experience this? |
Mild nosebleeds, dry or irritated nose or throat | If any of these become troublesome, speak with your doctor |
Headache | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
If you experience any other symptoms which you think may be due to ipratropium nasal spray, discuss them with your doctor or pharmacist.
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Before using ipratropium nasal spray
Back to contentsTo make sure this is the right treatment for you, before you start using ipratropium nasal spray it is important that your doctor knows:
If you have problems with your kidneys or prostate gland, or if you have any difficulty passing urine.
If you have increased pressure in your eye (glaucoma).
If you have cystic fibrosis.
If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to a medicine.
If you are pregnant or breastfeeding.
How to use ipratropium nasal spray
Back to contentsUse ipratropium nasal spray exactly as your doctor tells you to. The usual dose is two sprays into each nostril, two or three times each day.
Before you use the spray for the first time, you will need to 'prime' the bottle by pumping the spray into the air until you see a fine mist. Make sure it is pointed away from your eyes as you do this.
Directions:
Blow your nose gently if needed.
Remove the protective cap from the spray.
Close one nostril by placing a finger against it
Put a finger on each side of the spray and then insert the nozzle into your other nostril. Tilt your head slightly forward and try to keep the bottle upright.
Press down on the spray, breathe in (sniff) through your nose, and then breathe out through your mouth. Repeat this process to use the spray for a second time.
Use the spray in your other nostril by repeating the steps above.
After you have finished, tilt your head backwards for a short while. This will allow the medicine to come into contact with the back of your nose.
Wipe the nozzle of the spray with a tissue, and then put the cap back on.
Getting the most from your treatment
Back to contentsBefore you start using the spray, read the manufacturer's printed information leaflet from inside the pack. It will give you a step-by-step guide of how to use the spray and will also give you a full list of the side effects which you may experience.
To avoid spreading infection from one person to another, nasal sprays should only be used by one person. Do not share the spray with other people.
Take care to avoid spraying ipratropium near to your eyes. If any of the spray accidentally gets into your eyes, wash it out with warm water for a few minutes.
How to store ipratropium nasal spray
Back to contentsKeep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Back to contentsImportant information about all medicines
Never use more than the prescribed dose. If you suspect that you or someone else might have had an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.
Frequently asked questions
Back to contentsIs ipratropium a steroid?
No, ipratropium is not a steroid. It is an anticholinergic bronchodilator that helps open the airways and make breathing easier.
Is ipratropium long or short-acting?
Ipratropium is a short-acting bronchodilator. It typically works for around 4 to 6 hours, so it is usually taken several times a day.
When is the best time to take ipratropium?
The best time to take ipratropium is exactly as prescribed by your doctor, usually at regularly spaced intervals throughout the day. For most people, this means every 6 to 8 hours to keep symptoms controlled.
Can ipratropium be used during pregnancy?
It is generally considered safe to use ipratropium during pregnancy when prescribed by a doctor. This is because very little is absorbed into the bloodstream.
How long does it take for ipratropium to start working?
Ipratropium usually starts working within 15 to 30 minutes after inhalation. Most people notice improved breathing within about 15 minutes.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
What kind of conditions cause a 'runny nose' that ipratropium can help with?
Ipratropium nasal spray is used to stop rhinorrhoea, commonly known as a 'runny nose'. This can be caused by an allergy or other factors like changes in atmosphere or temperature.
Is it important to 'prime' the nasal spray before every use?
No, you only need to 'prime' the bottle before you use the spray for the first time. This involves pumping the spray into the air until a fine mist appears, ensuring it's pointed away from your eyes.
Can I use ipratropium nasal spray if I also have breathing problems?
Ipratropium is also available as an inhaler or nebules for treating breathing problems. However, this nasal spray is specifically for a runny nose. There's a separate leaflet called 'Ipratropium - a bronchodilator' for details on its use for breathing issues.
What should I do if the nasal spray accidentally gets into my eyes?
If any of the spray accidentally gets into your eyes, you should wash it out immediately with warm water for a few minutes.
Why shouldn't I share my ipratropium nasal spray with others?
To prevent the spread of infection from one person to another, nasal sprays should only be used by one individual. You should not share your spray with other people.
What is the recommended storage for ipratropium nasal spray?
You should store ipratropium nasal spray in a cool, dry place, keeping it away from direct heat and light. Ensure it is also kept out of the reach and sight of children.
Further reading and references
- Manufacturer's PIL, Rinaspray® 21 micrograms per metered dose Nasal Spray solution; Sanofi, The electronic Medicines Compendium. Dated December 2022.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 19 May 2029
19 Apr 2026 | Latest version

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