Can I take Apixaban and Bisoprolol together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no direct interaction between apixaban and bisoprolol. They work in different ways and do not interfere with how the body processes each other.
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Why this happens
Apixaban is an anticoagulant (blood thinner) that works by blocking a clotting factor called Factor Xa. Bisoprolol is a beta-blocker that slows the heart rate and lowers blood pressure. They are processed by different pathways in the liver and kidneys, and their primary effects do not overlap in a way that causes harm.
What you should do
You can safely take these two medicines together as prescribed by your doctor. It is common for these drugs to be prescribed together for conditions like atrial fibrillation. Always ensure your doctor knows all the medications you are taking, and do not stop taking either medicine without medical advice.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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