Naproxen tablets for pain and inflammation

About naproxen

Naproxen is a type of anti-inflammatory painkiller called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'.

It is used to treat painful conditions such as arthritis, sprains and strains, backache, period (menstrual) cramps, and gout pain.

Naproxen is available on prescription. Short courses of tablets for the treatment of period pain are also available to buy at pharmacies.

Naproxen works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins.

Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Common side effects of naproxen are:

• Stomach pain.

• Indigestion.

• Heartburn (reflux)

• Feeling sick.

• Being sick.

• Dizziness.

• Headache.

• Diarrhoea.

• Constipation.

You will find a full list in the manufacturer's information leaflet supplied with your medicine.

The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to this medicine, call your doctor or pharmacist for further advice.

Some medicines aren’t suitable for everyone. Before taking naproxen, your doctor or pharmacist needs to know:

• If you have asthma or any other allergic disorder.

• If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.

• If you are pregnant, trying for a baby, or breastfeeding.

• If you are over 65 years of age.

• If you have liver problems or kidney disease.

• If you have a heart condition, are at higher risk of heart attack, or have had a problem with your blood vessels or circulation.

• If you have high blood pressure.

• If you have ever had blood clotting problems.

• If you have high blood sugar or cholesterol levels.

• If you are a smoker.

• If you have a connective tissue disorder, such as systemic lupus erythematosus (an inflammatory condition also called lupus, or SLE).

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

• If you have ever had an allergic reaction to aspirin or other NSAID (such as indometacin, diclofenac, and ibuprofen), or to any other medicine.

• Before you start taking naproxen, read the manufacturer's printed information leaflet from inside the pack for information about your tablets and a full list of side effects which you may experience from taking them.

• Make sure you take the tablets exactly as your doctor or pharmacist tells you to:

  • Long-term conditions (such as arthritis): 500 mg-1 g daily, as one or two doses.

  • Short-term pain (muscle pain, sprains, period pain): usually 250 mg, taken 3-4 times daily. First dose may be 500 mg.

  • For gout, the usual dose is 750 mg for the first dose, and then 250 mg every eight hours until the attack has passed.

  • If you have bought naproxen over the counter for period pain, take 250 mg three times daily, for a maximum of three days.

  • The dose of Vimovo® is one tablet twice daily before meals.

  • Doses for children depend upon the age of the child.

• Take with food, milk, or water to reduce stomach upset (except Vimovo®, which should be taken 30 minutes before a meal).

• Some brands of naproxen are specially coated (enteric-coated (EC) tablets) to protect your stomach from irritation. Do not chew or break the tablets, as this will stop the coating from working properly.

• For enteric-coated (EC) tablets, avoid antacids 2 hours before and after taking them.

• If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses together.

• Your doctor will prescribe the lowest dose for the shortest time to reduce side effects.

• For long-term use you may be given another medicine to protect your stomach, or a combination product such as Vimovo®, which includes stomach protection.

• Keep regular appointments with your doctor, especially if you are taking naproxen long term.

• If you have asthma and develop wheezing or breathing problems, stop taking naproxen and see your doctor as soon as possible.

• Check with a pharmacist before taking other medicines. Do not take naproxen with other anti-inflammatory painkillers, including some cold and flu remedies.

• If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.

How long does it take for naproxen to work?

Naproxen usually starts to work within 1-2 hours of taking it, with the effects typically lasting for 8 to 12 hours. For chronic inflammation, pain and swelling usually begin to improve after a week of regular use.

Can you drink alcohol with naproxen?

Yes, you can drink alcohol with naproxen, however it can increase the risk of stomach irritation and bleeding. It is best to avoid or limit alcohol until your treatment is finished.

Is it safe to take naproxen during pregnancy?

Naproxen is not recommended during pregnancy, especially after 20 weeks, as it may harm the unborn baby. Only take it if your doctor specifically advises it.

Can you take paracetamol with naproxen?

Yes. You can take paracetamol with naproxen for pain relief. Do not combine naproxen with other anti-inflammatory painkillers.

Is naproxen addictive?

No. Naproxen is not addictive and does not cause dependence when taken as directed.