Can I take Devil's claw and Rosehip together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Both devil's claw and rosehip have natural blood-thinning properties. Taking them together might increase the risk of bruising or bleeding more easily. Additionally, both are used to reduce inflammation, which could lead to an increased effect on the stomach lining.
Why this happens
This is a pharmacodynamic interaction. Devil's claw may inhibit certain enzymes (COX-2) and rosehip contains compounds that can affect how platelets clump together. When used together, these effects can add up (additive effect), potentially slowing down blood clotting more than either supplement would on its own.
What you should do
It is generally best to use caution when combining these two supplements. If you decide to take both, watch for signs of easy bruising, nosebleeds, or bleeding gums. If you are scheduled for surgery or are already taking prescribed blood-thinning medications (like warfarin or aspirin), you must speak to your doctor before using this combination.
Important precautions
Stomach ulcers or gallstones
Devil's claw can increase stomach acid and stimulate bile production, which may worsen stomach ulcers, duodenal ulcers, or gallstones.
Diabetes
Devil's claw may lower blood sugar levels; you must monitor your blood glucose closely as your diabetes medication dosage may need adjustment.
Heart rhythm disorders (arrhythmias)
Devil's claw can affect heart rate and blood pressure; use with caution if you have a heart condition or take blood pressure medication.
Taking blood-thinning medication (e.g., warfarin)
Both supplements may increase the risk of bleeding or interfere with how your blood clots. You must have your clotting levels (INR) monitored more closely if you start taking these.
Food and drink warnings
Alcohol
It is best to avoid or strictly limit alcohol when taking Devil's Claw. Devil's Claw can increase the production of stomach acid, and alcohol is a known stomach irritant. Combining them may increase the risk of stomach upset, irritation, or gastric ulcers. Additionally, both substances are processed by the liver; combining them may increase the strain on liver function.
It is best to avoid or strictly limit alcohol when taking rosehip supplements. While there is no direct interaction, both alcohol and high doses of rosehip can put strain on the liver or kidneys in certain individuals, and alcohol may worsen the inflammatory conditions rosehip is often used to treat.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published

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