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Most people with COVID-19 infection (SARS CoV-2 infection) feel better within a few days or weeks and recover completely within 12 weeks of the infection. However, some people have ongoing symptoms that remain for weeks, months, or longer, which is usually called "long COVID". For some, these long-term effects of COVID-19 can be debilitating. These effects can be very different from person to person, and it seems likely that there are different 'types' of long COVID, or different syndromes, which might behave in different ways.

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What is long COVID?

Most people with COVID-19 infection (SARS CoV-2 infection) feel better within a few days or weeks and recover completely within 12 weeks of the infection. However, some people have ongoing symptoms that remain for weeks, months, or longer, which is usually called "long COVID". For some, these long-term effects of COVID-19 can be debilitating. These effects can be very different from person to person, and it seems likely that there are different 'types' of long COVID, or different syndromes, which might behave in different ways.

Long COVID was first identified in 2020, during the early stages of the COVID-19 pandemic, and, like any recently identified condition, there is much that is not yet fully understood about it. This includes the definition of long COVID, for which there is no clear international consensus.

In the UK, the National Institute for Health and Care Excellence (NICE), Scottish Intercollegiate Guidelines Network (SIGN) and Royal College of General Practitioners (RCGP) have described two conditions, both of which are considered 'long COVID':

  • Ongoing symptomatic COVID-19: signs and symptoms of COVID-19 from 4 weeks to up to 12 weeks.

  • Post-COVID-19 syndrome: signs and symptoms developing during, or after, COVID-19 infection, that continue for more than 12 weeks and are not explained by an alternative diagnosis.

Whilst long COVID has only recently been described, in some cases it shares similar features to myalgic encephalitis/chronic fatigue syndrome (ME/CFS). Knowledge of the causes and treatment of ME/CFS may help us understand long COVID, and vice versa.

How long does long COVID last?

The length of symptoms varies a lot from person to person. Based on the UK’s Office for National Statistics (ONS) data, about 1 in 10 people who get COVID-19 still have symptoms after five weeks, and, amongst those people, just over two thirds recover by twelve weeks.

People who are still feeling unwell with long COVID at 12 weeks after the initial infection may still improve over the next weeks or months. However, in some people, the symptoms do not resolve completely, and have remained for years, so far. In these people, long COVID seems to behave more like a long-term condition, and their symptoms may remain at a constant level, with flare-ups from time to time.

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What are the symptoms of long COVID?

People with long COVID can have a wide variety of symptoms. None of these symptoms occurs only in long COVID; other conditions can cause these as well. It's important to speak to a healthcare professional, such as your GP, if these symptoms have lasted for 12 weeks, if they are severe, or if you are worried about them, to explore other causes.

Symptoms of long COVID include:

In young people and children with long COVID, shortness of breath, chest pains, coughing, palpitations, and pains on breathing seem to be less common than in adults with long COVID.

Is long COVID contagious?

Whilst COVID-19 infection is very contagious, long COVID itself is not contagious. However - like anyone - people with long COVID can catch COVID-19 infection again. If they do, they can spread COVID-19 to other people and should follow the local public health guidance to reduce the risk of spreading it to others. See the COVID-19 leaflet for more information.

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What causes long COVID?

We are still learning more and more about long COVID. There isn’t yet a clear explanation for why some people recover completely from COVID-19 (or have no symptoms at all), and yet others develop long COVID. It's unlikely that there will be one simple answer. It may be that multiple different things cause COVID-19, and that these may be different from person to person.

Current theories are that the following might be implicated in long COVID:

  • Organ damage that occurs during the initial infection with COVID-19. We know that COVID-19 infection, and the body's response to it, can cause various problems, such as heart attacks, strokes, and lung damage, and these can have long-lasting effects. However, this on its own does not fully explain long COVID. Some people who had 'mild' symptoms in the initial phase of COVID-19 infection - without signs of organ damage - develop long COVID, and there is further research that suggests there may be other ongoing issues at play in people with long COVID.

  • Ongoing inflammation and autoimmune problems. Inflammation describes the body's response to infections and injuries, and is usually a good thing for recovering from them. However, inflammation can also cause major problems if the body uses it in the wrong place or for too long; long-lived ('chronic') inflammation has been linked to lots of other conditions. In long COVID, there is some evidence of long-lasting inflammation - this could cause problems in many areas, such as causing nerve damage, muscle weakness and wasting, and heart and lung damage. Some have suggested that COVID-19 infection could trigger the development of autoimmune problems in some people, ie conditions where the body's immune system mistakenly attacks normal body parts and organs.

  • Persistent infection with the SARS-CoV-2 virus. Some researchers have found evidence of the virus that causes COVID-19 in the organs of people with long COVID, even months after the initial infection. If the virus (or fragments of it) remains in people with long COVID, it could cause organ and tissue damage - either directly, or by provoking the body's inflammation response.

  • Issues with blood clotting. We know that COVID-19 infection is linked to a higher risk of developing blood clots within the body - for example, blood clots in the lungs (pulmonary emboli) and legs (deep vein thromboses). Some researchers have reported finding tiny 'microclots' in the blood of people with long COVID. They suggest that these microclots may get stuck in the blood vessels supplying the lung (and possibly elsewhere), causing organ damage and problems with organ function. (It hasn't yet been shown that these microclots are the cause of long COVID - it's possible that something else is causing both long COVID and microclots to form.)

  • Psychological aspects of serious and long-term illness. Symptoms of anxiety and depression are common in people with long COVID. We have known for some time that people who were critically ill and survived intensive care can be left with post-traumatic stress disorder-like symptoms. Being chronically ill with long COVID can cause symptoms of depression and anxiety. "Mental" and "physical" health are often thought of as separate issues, but lots of evidence shows the two are very closely linked; poor mental health can lead to poor physical health, and vice versa. Psychological distress alone does not explain why people get long COVID, but is certainly a consequence of the condition, and may increase the impact of symptoms for some.

What are the risk factors for long COVID?

Anyone can get long COVID, and we don't yet understand why some people develop it, and others don't. Higher rates of long COVID have been reported in the following groups:

  • People who have not been fully vaccinated against COVID-19.

  • Women.

  • Older age groups; in the UK's ONS data, long COVID symptoms were most common in the 50- to 69-age group. However, people of all ages can get long COVID.

  • People with other long-term medical conditions.

  • People with overweight or obesity.

Is there a test for long COVID?

Currently, there is no specific test for long COVID. The diagnosis is made by having symptoms of long COVID that occurred after a probable COVID-19 infection, with other causes of the symptoms having been ruled out.

Healthcare professionals should offer appropriate tests to look for other causes of long COVID symptoms. Each person's symptoms and examination findings will determine which tests might be helpful, and these will be different from person to person.

Tests that might be done, depending on what the signs and symptoms are, include:

  • Urgent tests, done in hospital, if clinicians are concerned that there is an immediately serious or life-threatening condition. If a heart attack or other types of heart damage are suspected, this might include an electrocardiogram (ECG) and a blood test looking for heart damage (troponin). If a blood clot in the legs or lungs is suspected, this might include: a blood test looking for blood clots (D-Dimer); an ultrasound scan of the leg veins; a CT scan of the arteries that supply the lungs.

  • A 'sit-to-stand' test, where people are asked to sit down and stand up repeatedly for a certain length of time - usually a minute. Blood oxygen levels and heart rate are measured at the beginning and end of the test. Some tests ask people to walk a certain distance as well. A drop in oxygen levels after exercise suggests the presence of lung problems.

  • A measurement of blood pressure and heart rate whilst lying down, and then after standing up, if there are symptoms suggestive of low blood pressure on standing, or of PoTS.

  • Blood tests. For example:

  • A resting ECG may be helpful if there are palpitations or other symptoms of heart or lung problems. Sometimes, an ECG monitor worn for 24 hours (or longer) may be useful if palpitations are ongoing but no cause is apparent from the resting ECG.

  • A chest X-ray will usually be offered if there are ongoing chest symptoms (eg cough or breathlessness) at 12 weeks after the initial COVID-19 infection.

  • Questionnaires to grade the severity of exhaustion, anxiety and depression.

  • Lung function tests to look for lung problems - at present, these are usually requested by hospital clinicians rather than GPs.

  • An ultrasound scan of the heart (echocardiogram) if the NT-proBNP blood test (looking for heart failure) is raised, or if there are other concerns about heart problems.

Other tests may be useful in specific situations, and more specialised tests may be requested by post-COVID clinics in hospitals, depending on each person's signs and symptoms.

Whilst there is ongoing research into the possibility that inflammation, autoimmunity, and microclots may be causing long COVID, the tests used in these research studies have not yet found a role in clinical practice. It's currently unclear how these tests can help either the diagnosis or treatment of people with long COVID. They are therefore generally not available in the NHS. It's possible that this may change in future, if good-quality evidence emerges to support their use.

How to treat long COVID

Much like with tests and investigations, there is no single treatment for long COVID, and treatments are guided by the symptoms that individuals are experiencing. Research is ongoing to find new, and hopefully more effective, treatment for people suffering with long COVID.

Current treatments include:

  • Treatment of any other conditions that are identified during assessment – for example, heart failure, PoTS, asthma or blood clots. See the relevant leaflets for more detail.

  • Pacing and conserving energy. People with tiredness, fatigue, and exhaustion from long COVID often find that over-exerting themselves causes symptoms to get worse. Activity management strategies can help to manage this. Symptom diaries can be helpful to monitor exhaustion and fatigue. A commonly used strategy is the "3 Ps":

    • Pace - manage activity and exertion to avoid becoming exhausted. This might involve: breaking tasks up into smaller chunks and doing them at different times throughout the day; taking regular breaks; stopping activities when feeling tired, rather than pushing through to the point of exhaustion; and doing things at a slower pace than before.

    • Plan - looking at tasks that have to be done that day, or that week, and spacing them out appropriately. For example, arranging to do tasks that are tiring on different days throughout the week, with rest days in between.

    • Prioritise - thinking about which tasks need to be done now, or in one go, and which can wait, be split up into chunks, or not done at all. Sometimes enlisting the help of other people can be helpful.

  • Breathing control exercises can be helpful for breathlessness, particularly for people with an altered breathing pattern, or dysfunctional breathing disorder.

  • Antihistamine medicines, for people with allergic-type symptoms (eg rashes).

  • Sleep hygiene for people with poor sleep, and, occasionally, a short course of sleeping tablets.

  • Smell training can help with changes in the sense of smell and taste. Nasal steroid sprays may possibly help as well.

  • Painkillers and gentle exercise can help with joint and muscle pain.

  • Rehabilitation programmes, with input from different healthcare professionals, such as physiotherapists, occupational therapists, and psychologists, can be helpful in supporting people to recover physically and emotionally from the effects of long COVID. There are also online platforms which can support self-management of long COVID, such as the Your COVID Recovery website (see Further Reading).

  • Mental health support, such as talking therapy, mindfulness, and medications can be helpful for people suffering from depression, anxiety, or other mental health conditions.

  • Sickness certification for work and school; some people may be too unwell to work at all for a time, and some people may need gradual returns to work with adjustments made by their employer.

  • COVID-19 vaccination. Research suggests that receiving COVID-19 vaccines is linked to an improvement in long COVID symptoms in some people, although in some studies, a small proportion of people experienced worsening of symptoms after vaccination. COVID-19 vaccination remains the most effective way of preventing serious illness and death from COVID-19 infection.

Many of the initial tests and treatments can be performed by GPs. In some cases - such as where the initial treatments have been unsuccessful, where symptoms are severe, or where the diagnosis is unclear, GPs may refer people with long COVID to an NHS 'post COVID' service. These generally involve input from multiple different specialists and healthcare professionals, aiming to provide comprehensive physical, cognitive and psychological assessments, arrange any additional diagnostic tests that may be needed, and support with treatment and rehabilitation.

There are other treatments that are being researched for long COVID; for example, the STIMULATE-ICP trial is looking at the use of combination antihistamines, blood-thinning drugs, and an anti-inflammatory drug for the treatment of long COVID. We don’' yet have good evidence that these drugs work for long COVID; evidence from well-designed research trials is needed to show whether these help people with long COVID, or whether they cause harm. At present, these treatments are not recommended for routine use in long COVID and should only be given as part of a research study.

Some treatments, such as those claiming to remove microclots, are being offered via private clinics, or outside the UK. There is little or no evidence that these are effective for treating long COVID, and these are therefore effectively experimental treatments. It's unclear currently whether these will help people with long COVID, or if they cause harm.

How to prevent long COVID

Vaccination against COVID-19 reduces the risk of developing long COVID - both by reducing the chances of catching COVID-19, and by reducing the risk of getting long COVID if you do catch COVID-19 - and is the best way to prevent serious illness and death from COVID-19.

See the separate article called The future of COVID-19 vaccinations for more details.

Other measures to avoid catching COVID-19 can help reduce the risk of getting COVID-19, and therefore the risk of developing long COVID. See the COVID-19 leaflet for more information.

We don’t currently have any reliable ways to prevent long COVID once someone has developed a COVID-19 infection.

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The information on this page is written and peer reviewed by qualified clinicians.

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