Can I take Ashwagandha and Vitamin B complex together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There are no known harmful interactions between ashwagandha and Vitamin B complex. In fact, they are often taken together to help manage stress and energy levels.
In this article:
Video picks for Drug interactions
It is usually safe to take ashwagandha and vitamin B complex together.
Ashwagandha is an adaptogenic herb that helps the body manage stress, while Vitamin B complex supports energy metabolism and nervous system function.
They work through different pathways in the body and do not interfere with how the other is absorbed, broken down, or used.
Continue reading below
How to take ashwagandha and vitamin B complex safely
Always follow the dosage instructions on the product labels.
If you have an underlying medical condition (such as a thyroid disorder or autoimmune disease), speak with your GP or a pharmacist before starting ashwagandha.
Important precautions
Back to contentsPregnancy
Do not use ashwagandha during pregnancy as it could cause a miscarriage.
Autoimmune diseases
Ashwagandha can stimulate the immune system, which may worsen the symptoms of autoimmune conditions such as lupus, rheumatoid arthritis, and MS.
Hyperthyroidism (overactive thyroid)
Ashwagandha can increase thyroid hormone levels. You must avoid it if you have an overactive thyroid, as it may worsen your condition or interfere with thyroid medications.
Scheduled Surgery
Stop taking ashwagandha at least 2 weeks before surgery; it can slow down the central nervous system and may dangerously increase the effect of anaesthesia.
Continue reading below
Food and drink warnings
Back to contentsAlcohol
It is best to avoid or strictly limit alcohol while taking ashwagandha as it has sedative properties and may enhance the effects of alcohol.
Combining them can lead to excessive drowsiness, impaired coordination, and slowed reaction times.
Dairy products
While dairy is a good source of B vitamins, taking a B complex supplement with a very large amount of dairy may slightly alter the absorption rate of Riboflavin (B2).
However, for most people, taking them together is acceptable unless specified by a doctor.
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Lion's mane and Shiitake together?
There are no known harmful interactions between Lion's Mane (Hericium erinaceus) and Shiitake (Lentinula edodes) mushrooms. Both are commonly consumed together as food or supplements.

Treatment and medication
Can I take Alogliptin and Atorvastatin together?
There are no known significant interactions between alogliptin and atorvastatin. It is generally considered safe to take these two medications together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.