Can I take Alendronic acid and Hard together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking alendronic acid with food, drinks (other than plain water), or other medicines significantly reduces the amount of medicine your body absorbs. This makes the treatment much less effective at strengthening your bones.
In this article:
Continue reading below
Why this happens
Alendronic acid is very poorly absorbed by the stomach. It binds easily to minerals and food particles, which prevents it from entering your bloodstream.
What you should do
Take your alendronic acid first thing in the morning on an empty stomach with a full glass of plain water. Wait at least 30 minutes before eating, drinking anything else, or taking any other medications. Stay upright (sitting or standing) during this time.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Magnesium and Bisoprolol together?
Taking magnesium and bisoprolol together can lead to an excessively slow heart rate or a significant drop in blood pressure. This may cause you to feel dizzy, lightheaded, or faint.

Treatment and medication
Can I take Idapamide and Ramipril together?
Taking indapamide and ramipril together can cause your blood pressure to drop too low, especially when you first start the combination. This can make you feel dizzy, lightheaded, or faint. It can also put extra strain on your kidneys.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.