Can I take Ezetimibe and Soft together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known interactions between ezetimibe and 'soft' (assuming this refers to soft drinks or carbonated beverages). Ezetimibe can be taken with or without food and does not have specific restrictions regarding non-alcoholic soft drinks.
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Why this happens
Ezetimibe is absorbed in the digestive tract and works locally in the small intestine to block cholesterol absorption. Soft drinks do not significantly alter the acidity of the stomach or the metabolic pathways (enzymes) that process ezetimibe.
What you should do
You can continue to take ezetimibe as prescribed. It is generally recommended to take your medication with water, but having a soft drink around the same time will not stop the medicine from working or cause a dangerous reaction. However, if 'soft' refers to a specific supplement or a different substance, please provide the full name.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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